Differential Expression for Mutated Status - Deseq2

This analysis investigates the expression differences between mutated and wild-type samples of a specific gene in a chosen tumor type using TCGA data. It employs the DESeq2 package to perform differential expression analysis, generating results saved as a text file. Visualization includes a heatmap of sample distances, PCA plots, a heatmap of the top 50 most variable genes, and an Enhanced Volcano plot to highlight significant gene expression changes. The results provide insights into the impact of mutations on gene expression within the tumor context.

For more details go to PANDA Documentation